Indian Society of Paediatric Radiology

UPCOMING EC MEETING
WHO WE ARE

The Indian Society of Paediatric Radiology (ISPR) was constituted to encourage and advance the knowledge and study of Paediatric Radiology in India since the vast knowledge of medical science needs to look at children and their medical problems in a different perspective. Diseases of children are completely different from adults including the anatomical make up of children differs from that of adults. India being the second most populous country in the world has a considerable paediatric age group population.

The society was formed so that dedicated paediatric radiologists can help, teach and promulgate the knowledge of this discipline to young and upcoming radiologists and help bridge the gap of such radiologists in our institutions which have a lack of specialized radioliogists. It is a non-profitable organization for the promotion of paediatric radiology in India and abroad to assist Government and Non-governmental agencies in all matters pertaining to paediatric radiology & medical diagnostic imaging, to encourage scientific work as well as to promote interaction among members of ISPR and allied specialists.

We hold one Mid-term National CME and one National Conference a year.
We publish an E-Newsletter twice a year for all our members.
We interact with other societies in India & in the world such as WFPI (World Federation of Paediatric Imaging) and AOSPR (Asian & Oceanic Society for Paediatric Radiology).
We have a dedicated team of office bearers with ISPR who help to carry the flag of ISPR forward.

QUIZ
FEB 2024 QUIZ
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Quiz Answer February 2024

Opsoclonus myoclonus ataxia syndrome (OMAS)

qaFeb2401.jpg ISPR Quiz Feb 2024

Normal MRI brain study. (A) Axial T2-FLAIR, (B) Axial, (C) Sagittal T1W, (D) Axial SWI MIP images



qaFeb2402A.jpg ISPR Quiz Feb 2024

(A) Axial , (C) coronal , (D) Sagittal T2W, (B) T1 post-contrast images showing a well-defined enhancing right suprarenal mass showing near homogenous T2 hyperintensity and no neural canal invasion (red arrows). Tumor was excised in-toto. Child is currently receiving immunomodulation therapy.



Discussion

Paraneoplastic syndrome secondary to neurogenic tumor. MRI brain was normal, but right suprarenal mass was found on spine screening and further characterized with MRI. Mass was FDG PET avid, but MIBG negative. Mass excised and histopathology revealed ganglioneuroblastoma.

qaFeb2403.jpg ISPR Quiz Feb 2024

(A) Axial CT, (B) fused 18F-FDG PET/CT image showing FDG avid right adrenal mass (red arrow).

  • Opsoclonus-myoclonus-ataxia syndrome (OMAS) is a rare disorder of the nervous system with onset usually in the second year of life.
  • Classically presents with a combination of characteristic eye movement disorder and myoclonus, in addition to ataxia, irritability, and sleep disturbance.
  • In around 50% of children presenting with OMAS, there is an underlying neuroblastoma. There is good evidence that OMAS is an immune-mediated condition that may be paraneoplastic in the context of neuroblastoma.
  • 18F-FDG PET/CT may be useful in patients with neurogenic tumors which are either weakly positive or negative on 123I-MIBG.

References

  • Gorman MP. Update on diagnosis, treatment, and prognosis in opsoclonus-myoclonus-ataxia syndrome. Curr Opin Pediatr 2010;22(6):745-750.
  • Rossor T, Yeh EA, Khakoo Y, Angelini P, Hemingway C, Irani SR et al. Diagnosis and Management of Opsoclonus-Myoclonus-Ataxia Syndrome in Children: An International Perspective. Neurol Neuroimmunol Neuroinflamm. 2022 Mar 8;9(3):e1153.
  • Sharp SE, Shulkin BL, Gelfand MJ, Salisbury S, Furman WL. 123I-MIBG scintigraphy and 18F-FDG PET in neuroblastoma. J Nucl Med. 2009 Aug;50(8):1237-43.

AFFILIATES